{"product_id":"new-product-275893","title":"MRPL18 polyclonal antibody","description":"\u003cp\u003eMitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L18 (mitochondrial ribosomal protein L18), also known as L18mt or HSPC071, is a 180 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with MRPs to mediate protein synthesis. The gene encoding MRP-L18 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45805083885848,"sku":"ABCBW03983","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_35716210-2348-4297-9327-cf8fb6b7c7a3.png?v=1689741019","url":"https:\/\/danabiosci.com\/products\/new-product-275893","provider":"Dana Bioscience","version":"1.0","type":"link"}