{"product_id":"new-product-275599","title":"IL1R2 polyclonal antibody","description":"\u003cp\u003eDecoy receptors are structurally incapable of activating signaling pathways, but act as anti-inflammatory agents by sequestering agonists for actual signaling complexes. The type II IL-1 receptor (IL-1RII) acts as a decoy receptor for the chemokine interleukin-1 (IL-1). Additionally, the soluble form of IL-1R accessory protein (IL-1R AcP) increases the affinity of binding of IL-1α and IL-1β to IL-1RII 100-fold, but does not increase the affinity for another antiinflammatory agent, IL-1R antagonist (IL-1Ra). The end result is a complex regulatory mechanism for IL-1 activated inflammation, whereby dexamethasone and other molecules inducing IL-1RII, function in an immunosupressive and anti-inflammatory manner.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":45804993216792,"sku":"ABCBW03689","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_c176f77a-8cdd-4246-911c-048ec860f687.png?v=1689740352","url":"https:\/\/danabiosci.com\/products\/new-product-275599","provider":"Dana Bioscience","version":"1.0","type":"link"}