{"product_id":"new-product-275590","title":"IL2RA polyclonal antibody","description":"\u003cp\u003eThe IL-2 receptor is amulticomponentcomplexconsisting of three subunits,α,\u003cbr\u003e\nβ and γ, each ofwhich isrequired for high-affinity binding of IL-2. Theαchain\u003cbr\u003e\nfunctions primarilyin binding IL-2, whereasthe β and γ chainscontribute to IL-2 binding and are essential to IL-2-induced activation ofsignaling pathways leading to T cell growth. Both IL-4R and IL-7R were initially described as single chain, high-affinityligand-binding cytokine receptors. However, it is now well established that the IL-2Rγ chain functions as a second subunit of the high affinityIL-4R and IL-7R receptors. Consequently, the originally described subunits of these latter receptors are nowreferred to asIL-4Rαand IL-7Rα, respectively,while the common subunit isreferred to as γc. Although the common γ chain enhancesligand binding in these three cytokine receptors, it has no capacityto bind these ligands on its own. There is evidence that the γcchain is also a subunit of IL-13R.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45804991938840,"sku":"ABCBW03680","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_1cc4b505-c7a4-40b7-9a60-e4a835d3247d.png?v=1689740333","url":"https:\/\/danabiosci.com\/products\/new-product-275590","provider":"Dana Bioscience","version":"1.0","type":"link"}