{"product_id":"new-product-275582","title":"BIRC2 polyclonal antibody","description":"\u003cp\u003eThree mammalian homologs of baculovirus p35, designated MIHA (mammalian IAP homolog A), MIHB and MIHC have been described. These three mammalian inhibitor of apoptosis proteins (IAPs) are designated XIAP, c-IAP1 and c-IAP2, respectively. XIAP, c-IAP1 and c-IAP2 share an N-terminal baculovirus IAP repeat (BIR) motif and a C-terminal RING finger. Although c-IAP1 and c-IAP2 do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. The interaction between the TRAF1\/TRAF2 heterocomplexes and c-IAPs is dependent on a functional BIR motif.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":45804989317400,"sku":"ABCBW03672","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_2f205d57-5b85-4ad9-b6f5-06275c94d44d.png?v=1689740318","url":"https:\/\/danabiosci.com\/products\/new-product-275582","provider":"Dana Bioscience","version":"1.0","type":"link"}