{"product_id":"new-product-275532","title":"ZNF462 polyclonal antibody","description":"\u003cp\u003eZinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1,thereby recruiting histone modifying proteins. ZNF462 (zinc finger protein 462) is a 2,506 amino acid protein that localizes to nucleus and is subject to posttranslational phosphorylation upon DNA damage, possibly by ATM or ATR.Containing twenty-seven C2H2-type zinc finger motifs and existing as multiple alternatively spliced isoforms, ZNF462 is encoded by a gene located on human chromosome 9q31.2. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects,and Familial dysautonomia, are both associated with chromosome 9.Notably, chromosome 9 encompasses the largest interferon family gene\u003cbr\u003e\ncluster.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Rat","offer_id":45804977946904,"sku":"ABCBW03622","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_cf5aee5c-869b-4fd7-b583-3928cc9d0722.png?v=1689740192","url":"https:\/\/danabiosci.com\/products\/new-product-275532","provider":"Dana Bioscience","version":"1.0","type":"link"}