{"product_id":"new-product-275465","title":"CATSPER1 polyclonal antibody","description":"\u003cp\u003eCatSper is an ion transport protein located on the surface of sperm cells. CatSper (for cation channel of sperm) is vital to cAMP-mediated calcium influx in sperm, sperm motility and fertilization. The gene that encodes CatSper maps to human chromosome 11q12.1. The 686 amino acid protein is a single, six-transmembrane-spanning protein of the voltage- dependent Ca2+ channel four-repeat structure and is expressed exclusively in the testis. In CatSper -\/- sperm, neither cAMP nor cGMP elicit a significant Ca2+ influx in both mutant and wild-type sperm. CatSper is localized to the sperm flagellum and CatSper -\/- mice show sluggish and less directed movements. CatSper is required to penetrate the egg, but is not required for egg activation.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45804965724440,"sku":"ABCBW03555","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_2c45fe39-ae73-4560-86f7-94c81589b64f.png?v=1689740034","url":"https:\/\/danabiosci.com\/products\/new-product-275465","provider":"Dana Bioscience","version":"1.0","type":"link"}