{"product_id":"new-product-275451","title":"EDEM1 polyclonal antibody","description":"\u003cp\u003eProteins expressed in the endoplasmic reticulum (ER) are subjected to a tight quality control. Terminally misfolded proteins in the endoplasmic reticulum (ER) are retrotranslocated to the cytoplasm and degraded by proteasomes through a mechanism known as ER-associated degradation (ERAD). EDEM (ER degradation-enhancing alpha-mannosidase-like) protein is a type II membrane protein that localizes to the ER and is directly involved in ERAD. EDEM targets misfolded glycoproteins for degradation in an N-glycan-dependent manner and extracts misfolded glycoproteins from the calnexin cycle. The human EDEM gene maps to chromosome 3p.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45804964217112,"sku":"ABCBW03541","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_25c077ef-0143-4e87-b3e8-be5adbda379a.png?v=1689740003","url":"https:\/\/danabiosci.com\/products\/new-product-275451","provider":"Dana Bioscience","version":"1.0","type":"link"}