{"product_id":"new-product-275261","title":"PROK1 polyclonal antibody","description":"\u003cp\u003eEndocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation,migration and fenestration in capillary endothelialcells derived from endocrine glands. EG-VEGF possesses a HIF-1 binding site; its expression isinduced by hypoxia and restricted to the steroidogenic glands(ovary,testis, adrenal and placenta). EG-VEGF expression is often complementary to the expression of VEGF,suggesting that these moleculesfunction in a coordinatedmanner. EG-VEGFis an example of a class of highly specificmitogensthat act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. EG-VEGFis expressed largely in one type of tissue and actsselectively on one type of endothelium. EG-VEGF, possiblythrough binding to a G protein-coupled receptor, resultsin the activation ofMAPK p44\/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation,migration and survival of responsive endothelialcells.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45804936855832,"sku":"ABCBW03351","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_96ca2234-43b2-49bd-aaa1-9c1feddc7231.png?v=1689739560","url":"https:\/\/danabiosci.com\/products\/new-product-275261","provider":"Dana Bioscience","version":"1.0","type":"link"}