{"product_id":"new-product-275204","title":"SCT polyclonal antibody","description":"\u003cp\u003eSecretin is a 27-amino acid hormone produced by specific endocrine cells, S cells, located in the mucosa of the proximal small intestine. Secretin is known to be a potent stimulus for the secretion of bicarbonate-rich pancreatic juice. Secretion of secretin is stimulated by the presence of either acidic pH or fatty acids in the duodenum. Secretin is synthesized as a larger precursor. The deduced amino acid sequence includes a signal peptide, an amino-terminal peptide, secretin itself, and a 72-amino acid carboxy-terminal peptide. Secretin stimulates ductal bile secretion by directly interacting with cholangiocytes. It stimulates exocytosis in cholangiocytes, which transport water mainly via the water channel aquaporin-1. Secretin deficiency may be implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion. The gene which encodes secretin maps to human chromosome 11p15.5.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45804930007320,"sku":"ABCBW03294","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_387d2f47-8d5f-413e-bff4-0e753842d974.png?v=1689739430","url":"https:\/\/danabiosci.com\/products\/new-product-275204","provider":"Dana Bioscience","version":"1.0","type":"link"}