{"product_id":"new-product-274802","title":"Rho D polyclonal antibody","description":"\u003cp\u003eUpon activation, the small GTPase Rho D (also designated RhoHP1 and ARHD) contributes to rearrangement of the actin cytoskeleton and cell surface and also governs endosome motility and distribution. The effects of Rho D antagonize those of its family member, Rho A, by dissasembling actin stress fibers normally enhanced by Rho A. Additionally, Rho D disengages focal adhesions, resulting in retardation of cell migration. Accordingly, transfection of a constitutively active form of Rho D (designated Rho D G26V) reverses the invasive phenotype of Gαolf induced cells, implying the possiblity of a therapeutic use for activated Rho D in counteracting tumor metastasis.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45804618809624,"sku":"ABCBW02892","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_8cfb8678-cb04-46ae-8be9-d4f4fc62e2ef.png?v=1689738524","url":"https:\/\/danabiosci.com\/products\/new-product-274802","provider":"Dana Bioscience","version":"1.0","type":"link"}