{"product_id":"new-product-274621","title":"Contactin-2 polyclonal antibody","description":"\u003cp\u003eContactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2\/NgCAM and Contactin 2\/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2\/Contactin 2) binding site is localized to the FNIII domain.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45804380094744,"sku":"ABCBW02711","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_14dc4856-7311-4e64-aba8-af4cad165817.png?v=1689738130","url":"https:\/\/danabiosci.com\/products\/new-product-274621","provider":"Dana Bioscience","version":"1.0","type":"link"}