{"product_id":"new-product-273786","title":"Caspase 12 (P99) polyclonal antibody","description":"\u003cp\u003eCed-3\/caspase-1, is composed of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, caspase-10, caspase-14, and caspase-5\/caspase-12. Ced-3\/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-5 (also designated TY or ICErelIII) can cleave its own precursor, an activity that requires the cysteine 245 residue. The mouse homolog of caspase-5 is designated caspase-12. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon and stomach, indicating that caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45803517837592,"sku":"ABCBW01876","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_902a795a-a037-4f95-a6fd-316792ff7aec.png?v=1689736067","url":"https:\/\/danabiosci.com\/products\/new-product-273786","provider":"Dana Bioscience","version":"1.0","type":"link"}