{"product_id":"new-product-273601","title":"NOC2L (I634) polyclonal antibody","description":"\u003cp\u003eGADD 153, a growth arrest and DNA damage-inducible gene, encodes a C\/EBP-related nuclear protein. This protein has also been designated C\/EBP-homologous protein (CHOP-10 or C\/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C\/EBP proteins to direct GADD 153 dimers away from “classical” C\/EBP binding sites, recognizing instead unique “nonclassical” sites. Thus, GADD 153 acts as a negative modulator of C\/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF\/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC2L is a 749 amino acid nuclear protein that may play a role in cell cycle regulation.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45803454234904,"sku":"ABCBW01691","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_b1c08d9b-db04-4874-9fcb-e5f58ee212f3.png?v=1689735617","url":"https:\/\/danabiosci.com\/products\/new-product-273601","provider":"Dana Bioscience","version":"1.0","type":"link"}