{"product_id":"new-product-273466","title":"CD179b (V26) polyclonal antibody","description":"\u003cp\u003eLambda 5 (also called immunoglobulin lambda-like polypeptide 1 or CD179b antigen) and VpreB comprise the surrogate light chain of the pre-B cell receptor complex. SL chain is also part of a quality control mechanism that tests a μ-chain for its ability to pair with conventional L chains. It can form Ig-like complexes with the heavy (H) chain, the DHJHC μ-protein or the p55 chain. Production of the surrogate light chain begins at the stage of pro-B cells, continues during the pre-B cell stage and halts at the immature B cell stage. Once pre-BCR is expressed, SL chain expression is turned off. As pre-B II cells proliferate, SL is diluted out, thus limiting pre-BCR formation. Lambda 5, a 22 kDa protein, is critical for B cell development in mammals. Expression of Lambda 5 is highest in liver, pre-B lymphocytes and bone marrow, the major source of B cell precursors.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45803416912152,"sku":"ABCBW01556","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_4df01c03-b4fc-4093-ad79-2983634babb8.png?v=1689735274","url":"https:\/\/danabiosci.com\/products\/new-product-273466","provider":"Dana Bioscience","version":"1.0","type":"link"}