{"product_id":"new-product-273226","title":"ERK8 (D171) polyclonal antibody","description":"\u003cp\u003eThe ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET\/PTC3 and, therefore, RET biological functions.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45803346362648,"sku":"ABCBW01316","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_b01d284e-6dd3-4412-94fb-5e28aa22d4ec.png?v=1689734654","url":"https:\/\/danabiosci.com\/products\/new-product-273226","provider":"Dana Bioscience","version":"1.0","type":"link"}