{"product_id":"new-product-273151","title":"Ksr2 (I694) polyclonal antibody","description":"\u003cp\u003eKinase suppressor of Ras (Ksr) and MAP kinase kinase kinase (MEKK3) are integral members of the MAP kinase pathway. Ksr is a conserved protein that positively regulates Ras signaling and may function as a scaffold for Raf, MEK and ERK. There are two types of Ksr proteins: Ksr-1 and Ksr-2. Ksr-2 plays a key role in Ras-mediated signaling during germline meiotic progression and functions redundantly with Ksr-1 during the development of the excretory system pathway, hermaphrodite vulva, and male spicules. Ksr-2 also functions as a negative regulator of the MEKK3-mediated activation of the MAP kinase pathways (specifically ERK and JNK) and of the NF˚B pathways, and it simultaneously inhibits MEKK3-mediated Il-8 production.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45803336237336,"sku":"ABCBW01241","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_3b6b69aa-ea94-451a-8852-b81b109fa55f.png?v=1689734482","url":"https:\/\/danabiosci.com\/products\/new-product-273151","provider":"Dana Bioscience","version":"1.0","type":"link"}