{"product_id":"new-product-273095","title":"HGK (R430) polyclonal antibody","description":"\u003cp\u003eSeveral mammalian kinases have been identified which exhibit sequence similarity to the Saccharomyces cerevisiae serine\/threonine kinase STE20. STE20 is involved in relaying signals from G-protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include NIK, KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, and GC kinase. NIK (Nck interacting kinase), like many of the STE20-like kinases, has been shown to activate the SAPK\/JNK stress response pathway. Both the kinase domain and the C-terminal regulatory domain of NIK are required for full activation. NIK interacts with MEKK1 and is thought to act upstream of MEKK1 in the SAPK\/JNK signaling pathway.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45803327521048,"sku":"ABCBW01185","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_b9964baf-8867-4917-ab58-4249365cf536.png?v=1689734347","url":"https:\/\/danabiosci.com\/products\/new-product-273095","provider":"Dana Bioscience","version":"1.0","type":"link"}