{"product_id":"new-product-272610","title":"PBK (I4) polyclonal antibody","description":"\u003cp\u003ePBK (PDZ binding kinase) belongs to the serine\/threonine protein kinase family. It is related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family and phosphorylates MAP kinase p38. It is active only in mitosis. When phosphorylated it forms a complex with TP53, leading to TP53 destabilization and attenuation of G2\/M checkpoint during doxorubicin-induced DNA damage. It makes a kinase-substrate complex with cdk1\/cyclin B1 and PRC1 on microtubules during mitosis, enhances the cdk1\/cyclin B1-dependent phosphorylation of PRC1 and thereby strongly promotes cytokinesis. It may play a role in the activation of lymphoid cells.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45803206705432,"sku":"ABCBW00700","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_0072b422-1226-4fdf-9363-4777c947a50d.png?v=1689733102","url":"https:\/\/danabiosci.com\/products\/new-product-272610","provider":"Dana Bioscience","version":"1.0","type":"link"}