{"product_id":"new-product-272144","title":"PD1 monoclonal antibody (Humanized)","description":"\u003cp\u003eThe humanized monoclonal anti-PD1 antibody can effectively block the combination between PDL1 and PD1, and will not cause HAMA reaction (anti mouse antibody response). Programmed cell death protein 1 (PD-1) (UniProt Q15116), is a type I single transmembrane protein encoded by the PDCD1 gene in human. T-cell activation is generally self-limited as activated T cells express receptors such as PD-1. Maintenance of peripheral tolerance by preventing the development of autoimmunity due to T lymphocytes specific for self-antigens is essential for homeostasis of the immune system. PD-1 can bind two different but related ligands, PDL-1 and PDL-2.PD-1 receptor and its ligands PD-L1 and PD-L2play a vital role in the induction and maintenance of peripheral tolerance. The humanized monoclonal anti-PD1 antibody has demonstrated durable antitumor activity.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Human \/ Human","offer_id":45803124621592,"sku":"ABCBW00234","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_aa622394-4cd1-446e-a5c5-9065b95def7a.png?v=1689731936","url":"https:\/\/danabiosci.com\/products\/new-product-272144","provider":"Dana Bioscience","version":"1.0","type":"link"}