{"product_id":"new-product-271961","title":"IL-4R\/CD124(Tyr497) polyclonal antibody","description":"\u003cp\u003eThe IL-2 receptor is a multicomponent complex consisting of three subunits, α,β and γ, each of which is required for high affinity binding of IL-2. The α chainfunctions primarily in binding IL-2, whereas the β and γ chains contribute toIL-2 binding and are essential to IL-2-induced activation of signaling pathwaysleading to T cell growth. Both IL-4R and IL-7R were initially described as single chain, high-affinity ligand-binding cytokine receptors. However, it is nowwell established that the IL-2Rγ chain functions as a second subunit of thehigh affinity IL-4R and IL-7R receptors. Consequently, the originally describedsubunits of these latter receptors are now referred to as IL-4Rα and IL-7Rα,respectively, while the common subunit is referred to as γc. Although the common γ chain enhances ligand binding in these three cytokine receptors, ithas no capacity to bind these ligands on its own. There is evidence that theγc chain is also a subunit of IL-13R.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45803091820824,"sku":"ABCBW00051","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_10f06090-6e72-4a09-84c8-e0dae703533c.png?v=1689731482","url":"https:\/\/danabiosci.com\/products\/new-product-271961","provider":"Dana Bioscience","version":"1.0","type":"link"}