{"product_id":"new-product-234648","title":"TCF-4\/12 (S616) polyclonal antibody","description":"\u003cp\u003eT cell factors (TCFs) comprise a family of DNA-binding transcriptional activators that are essential for lymphoid cell development. These transcription factors are activated by the Wnt-1 and Wingless pathways and are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, which mediates DNA binding. TCF-4 mainly localizes in the cytoplasm and is transported into the nucleus directly bound to β-catenin in a cooperative manner. This TCF-4\/β-catenin complex induces expression of Wnt target genes, including multiple cancer-associated genes.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47665604329752,"sku":"BS1934","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_b18f64f5-febe-44b6-854e-0ad0ae6960fd.jpg?v=1707517957","url":"https:\/\/danabiosci.com\/products\/new-product-234648","provider":"Dana Bioscience","version":"1.0","type":"link"}