{"product_id":"new-product-233552","title":"X11γ (R401) polyclonal antibody","description":"\u003cp\u003eAmyloid β precursor protein (β APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The amyloid β precursor is known to interact with several proteins, including the G heterotrimetric protein, APP-BP1, and X11. The neuronal, transmembrane protein X11 is known to bind to the amyloid β precurser protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular β APP and slowing β APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of β APP. Multiple splice varitents of X11 have been identified, including X11 α, β and γ (also known as Mint 1, 2 and 3, respectively).\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47664945430808,"sku":"BS3806","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_0d078927-9823-4ee5-8334-d75e2ac9b245.jpg?v=1707512951","url":"https:\/\/danabiosci.com\/products\/new-product-233552","provider":"Dana Bioscience","version":"1.0","type":"link"}