{"product_id":"new-product-233293","title":"ZNF801 polyclonal antibody","description":"\u003cp\u003eThe Myc-associated zinc finger protein MAZ (also designated ZF87, and Pur-1 in mouse) is a transcription factor that participates in both the initiation and termination of transcription of target genes. MAZ functions as a true transcriptional repressor in that it represses transcription independent of the c-Myc promoter. Both MAZ and SP1 bind to the parathyroid hormone (PTH)\/ PTH-related peptide receptor promoter, thereby influencing the cell-specific expression of its gene product. MAZ and SP1 also regulate expression from the serotonin 1A receptor gene promoter, suggesting that MAZ may act on a variety of promoters through G-C rich sequences, which serve as binding sites for the SP1 family of transcription factors. Competition between SP1 and MAZ control tissue-specific expression of the PNMT gene. The interaction of MAZ with the transcriptional repressor FAC1 may affect gene regulation in neurodegeneration. MAZ also acts as a growth suppressor protein, in part by affecting the levels of key cell cycle regulatory proteins such as cyclin A and E.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664263495960,"sku":"BS5792","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_44b1b354-c103-42c3-bf1e-2edc3c0519f3.jpg?v=1707511685","url":"https:\/\/danabiosci.com\/products\/new-product-233293","provider":"Dana Bioscience","version":"1.0","type":"link"}