{"product_id":"new-product-233208","title":"Rho D polyclonal antibody","description":"\u003cp\u003eUpon activation, the small GTPase Rho D (also designated RhoHP1 and ARHD) contributes to rearrangement of the actin cytoskeleton and cell surface and also governs endosome motility and distribution. The effects of Rho D antagonize those of its family member, Rho A, by dissasembling actin stress fibers normally enhanced by Rho A. Additionally, Rho D disengages focal adhesions, resulting in retardation of cell migration. Accordingly, transfection of a constitutively active form of Rho D (designated Rho D G26V) reverses the invasive phenotype of Gαolf induced cells, implying the possiblity of a therapeutic use for activated Rho D in counteracting tumor metastasis.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664176595224,"sku":"BS5898","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_c1ebcc0a-c39c-4223-9c2e-0a9db0067459.jpg?v=1707511298","url":"https:\/\/danabiosci.com\/products\/new-product-233208","provider":"Dana Bioscience","version":"1.0","type":"link"}