{"product_id":"new-product-232887","title":"Profilin-2 polyclonal antibody","description":"\u003cp\u003eProfilins (Profilin-1, Profilin-2 and Profilin-3) act as nucleotide exchange factors that use ATP to charge Actin, a process that regulates Actin polymerization by subsequently sequestering the Actin monomer. Profilin-2, also known as PFN2 or PFL, is a 140 amino acid protein that is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the Profilin family, Profilin-2 functions as an Actin monomer-binding protein that influences the structure of the cytoskeleton by regulating Actin polymerization in response to extracellular signals. High levels of Profilin-2 inhibit Actin polymerization, while lower levels enhance Actin polymerization, suggesting that the expression of Profilin-2 is regulated by the need for polymerization within the cell. Two isoforms of Profilin-2 exist due to alternative splicing events.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664092348696,"sku":"BS60364","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_0c727f4b-4ee7-4ce1-bedd-c9a112f3efcc.jpg?v=1707509869","url":"https:\/\/danabiosci.com\/products\/new-product-232887","provider":"Dana Bioscience","version":"1.0","type":"link"}