{"product_id":"new-product-232845","title":"SCT polyclonal antibody","description":"\u003cp\u003eSecretin is a 27-amino acid hormone produced by specific endocrine cells, S cells, located in the mucosa of the proximal small intestine. Secretin is known to be a potent stimulus for the secretion of bicarbonate-rich pancreatic juice. Secretion of secretin is stimulated by the presence of either acidic pH or fatty acids in the duodenum. Secretin is synthesized as a larger precursor. The deduced amino acid sequence includes a signal peptide, an amino-terminal peptide, secretin itself, and a 72-amino acid carboxy-terminal peptide. Secretin stimulates ductal bile secretion by directly interacting with cholangiocytes. It stimulates exocytosis in cholangiocytes, which transport water mainly via the water channel aquaporin-1. Secretin deficiency may be implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion. The gene which encodes secretin maps to human chromosome 11p15.5.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664085106968,"sku":"BS60409","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_71289783-59ca-41b6-bd0b-dd62d45ce5e3.jpg?v=1707509708","url":"https:\/\/danabiosci.com\/products\/new-product-232845","provider":"Dana Bioscience","version":"1.0","type":"link"}