{"product_id":"new-product-232803","title":"BIRC2 polyclonal antibody","description":"\u003cp\u003eThree mammalian homologs of baculovirus p35, designated MIHA (mammalian IAP homolog A), MIHB and MIHC have been described. These three mammalian inhibitor of apoptosis proteins (IAPs) are designated XIAP, c-IAP1 and c-IAP2, respectively. XIAP, c-IAP1 and c-IAP2 share an N-terminal baculovirus IAP repeat (BIR) motif and a C-terminal RING finger. Although c-IAP1 and c-IAP2 do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. The interaction between the TRAF1\/TRAF2 heterocomplexes and c-IAPs is dependent on a functional BIR motif.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664066789656,"sku":"BS60459","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_64d469d2-c469-4d54-83de-0c82bd3493d2.jpg?v=1707509542","url":"https:\/\/danabiosci.com\/products\/new-product-232803","provider":"Dana Bioscience","version":"1.0","type":"link"}