{"product_id":"new-product-232750","title":"TNFRSF17 polyclonal antibody","description":"\u003cp\u003eThe B cell maturation protein (BCMA), also designated BCM and tumor necrosis factor receptor superfamily, member 17, is a type I integral membrane protein located on chromosome band 16p13.1 that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664041853208,"sku":"BS60527","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_072ad967-92b2-4874-ab72-12cb3dbb29a4.jpg?v=1707509286","url":"https:\/\/danabiosci.com\/products\/new-product-232750","provider":"Dana Bioscience","version":"1.0","type":"link"}