{"product_id":"new-product-232740","title":"CLEC6A polyclonal antibody","description":"\u003cp\u003eTogether, Dectin-1 and Dectin-2 make up the unique subfamily of dendritic cell-associated C-type lectins. Dectin-2 is expressed on antigen-presenting cells, where it interacts with its putative ligands on T cells. That interaction may deliver co-stimulatory signals in naive T cells. Dectin-2 expression is upregulated during monocyte activation and maturation at inflammatory lesions. Broadband UV-B upregulates Dectin-2 expression in Langerhans cells by activating the Dectin-2 gene promoter, suggesting that this protein plays a crucial role in the mediation of UV-induced immunosuppression. In cattle, Dectin-2 expressed by dendritic cells may also play a role in the recognition of invading antigens in lymph nodes. Dectin-2 functions as a pattern recognition receptor for fungi that activates signaling through FcR© to induce innate immune responses.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664037265688,"sku":"BS60545","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_b7725730-1327-4c0e-b533-1123512b28c6.jpg?v=1707509258","url":"https:\/\/danabiosci.com\/products\/new-product-232740","provider":"Dana Bioscience","version":"1.0","type":"link"}