{"product_id":"new-product-232657","title":"TRMT11 polyclonal antibody","description":"\u003cp\u003eTRM11 (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) is a 463 amino acid protein that belongs to the methyltransferase superfamily. TRM11 is believed to be the catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs. The gene encoding TRM11 maps to a region on chromosome 6 that is shared by seven other genes, which have been linked to diffuse panbronchiolitis. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47664009609496,"sku":"BS60656","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_1d6051f4-6af1-4e80-9f7c-f59746b594e9.jpg?v=1707508866","url":"https:\/\/danabiosci.com\/products\/new-product-232657","provider":"Dana Bioscience","version":"1.0","type":"link"}