{"product_id":"new-product-232571","title":"BAI3 polyclonal antibody","description":"\u003cp\u003eBrain-specific angiogenesis inhibitors, including BAI-1, BAI-2, and BAI-3, are integral membrane proteins belonging to the G-protein coupled receptor 2 family. In addition to inhibiting angiogenesis in the brain, BAI proteins are also expressed in the heart, thymus, skeletal muscle, and a variety of cell lines. BAI-3 is predominantly expressed in brain. Reduced expression may be observed in some glioblastoma cell lines suggesting that BAI-3 may function in the suppression of glioblastoma. Localization of BAI-3 in most neurons of the cerebral cortex is analogous with BAI-1 and BAI-2 expression in the adult brain, but varies in the developing brain. The activity of brain-specific angiogenesis inhibitor proteins has been inversely correlated with vascularization in some cancer tissues. BAI-3 activity may be significant in the early phases of ishemia-induced brain angiogenesis and in brain tumor progression. A better understanding of the anti-angiogenic activity of these BAIs may offer potential therapeutic benefits.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47663964881176,"sku":"BS60780","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_f62feb81-4f48-4249-906b-23cf2210d9d2.jpg?v=1707508467","url":"https:\/\/danabiosci.com\/products\/new-product-232571","provider":"Dana Bioscience","version":"1.0","type":"link"}