{"product_id":"new-product-232482","title":"CCR4 polyclonal antibody","description":"\u003cp\u003eC-C or β chemokine family members are characterized by a pair of adjacent\u003cbr\u003e\ncysteine residues and serve as potentchemoattractants and activators of monocytes and T cells. C-C chemokine receptor family members include CKR-1,CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7 and the Duffy blood group antigen. Each of these receptors are G protein-coupled,seven pass\u003cbr\u003e\ntransmembrane domain proteins whose major physiological role is to function\u003cbr\u003e\nin the chemotaxis of T cells and phagocytic cells to areas of inflammation.\u003cbr\u003e\nHowever, this receptor family has also been shown to facilitate viral infection.\u003cbr\u003e\nCKR-4 (C-C chemokine receptor type 4), also known as CCR4 or CMKBR4, is\u003cbr\u003e\na 360 amino acidmulti-pass membrane protein that localizes to the cell membrane and belongs to the C-C chemokine receptor family. Expressed at high levels in peripheral blood leukocytes and thymustissue, CKR-4 functions as a high affinity receptor for C-C type chemokines and is thought to be involved\u003cbr\u003e\nin hippocampal-neuron survival.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47663919825176,"sku":"BS60964","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_0aa88cdf-c013-4fdb-95dc-3b936880373e.jpg?v=1707508035","url":"https:\/\/danabiosci.com\/products\/new-product-232482","provider":"Dana Bioscience","version":"1.0","type":"link"}