{"product_id":"new-product-232476","title":"IL36RN polyclonal antibody","description":"\u003cp\u003eIL-1 (Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors, NFκB and AP-1, thereby promoting host response to injury or infection. The IL-1 superfamily is comprised of several ligands and receptors. IL-1F5, also known as IL-1δ, IL-1 like protein 1 (IL-1L1), IL-1HY1, IL-1ra (receptor antagonist) homolog 1 or IL-1 related protein 3 (IL-1rp3), is a secreted ligand belonging to this superfamily. IL-1F5 is expressed in monocytes and macrophages and is activated by endotoxins. It shares 47% sequence identity with IL-1ra and similarly lacks the loop between the fourth and fifth ∫-strands. IL-1F5 acts as an antagonist, inhibiting the IL-1F9 activation of NFκB. Similar to other family members, IL-1F5 can be regulated by bacterial lipopolysaccharide (LPS).\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Rat","offer_id":47663916122392,"sku":"BS60972","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_93779e2d-854f-43ca-a07c-9cccfd1380aa.jpg?v=1707508011","url":"https:\/\/danabiosci.com\/products\/new-product-232476","provider":"Dana Bioscience","version":"1.0","type":"link"}