{"product_id":"new-product-232471","title":"IL17D polyclonal antibody","description":"\u003cp\u003eCytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. The proinflammatory cytokine Interleukin 17D (IL-17D), also known as IL-27, is the largest member of the IL-17 family of cytokines. It is produced by CD4+ T cells and is predominantly expressed in brain, lung, heart, adipose tissue, pancreas and skeletal muscle. IL-17D regulates the production of other cytokines in endothelial cells, including IL-6, IL-8 and GM-CSF. It may play a role in the activation of the endothelium, which is the site of attachment for migrating immune cells. In addition, IL-17D may play a role in the amplification of a local immune response.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47663914909976,"sku":"BS60982","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_e52b741c-f736-48ae-8e39-6c9971732cc0.jpg?v=1707507988","url":"https:\/\/danabiosci.com\/products\/new-product-232471","provider":"Dana Bioscience","version":"1.0","type":"link"}