{"product_id":"new-product-232291","title":"VGLL2 polyclonal antibody","description":"\u003cp\u003eVgl-2 (Transcription cofactor vestigial-like protein 2), also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus.Overexpression of Vgl-2 in MYOD-transfected 10T1\/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47663706046744,"sku":"BS61467","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_1f93ea13-f341-4e19-aead-26d0b587029b.jpg?v=1707507111","url":"https:\/\/danabiosci.com\/products\/new-product-232291","provider":"Dana Bioscience","version":"1.0","type":"link"}