{"product_id":"new-product-232220","title":"CIDEB polyclonal antibody","description":"\u003cp\u003eThe DNA fragmentation factor (DFF) is involved in the caspase-3 apoptotic\u003cbr\u003e\npathway. DFF is composed of two subunits, a 45 kDa subunit called DFF-45\u003cbr\u003e\n(also designated ICAD, for inhibitor of CAD), and CPAN (caspase-activated\u003cbr\u003e\nnuclease), also designated CAD (caspase-activated deoxyribonuclease).\u003cbr\u003e\nCPAN is a DNase that is responsible for DNA degradation during apoptosis.\u003cbr\u003e\nCPAN is inhibited by DFF-45. Caspase-3 acts to dissociate CPAN from DFF-45,\u003cbr\u003e\nallowing CPAN to enter the nucleus and degrade DNA. CIDE-A and CIDE-B\u003cbr\u003e\nhave been identified as proteins that share homology with the N-terminal\u003cbr\u003e\nregion of DFF-45. Like CPAN, CIDE-A and CIDE-B promote cell death and\u003cbr\u003e\nDNA fragmentation and are inhibited by DFF-45.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47663612952856,"sku":"BS61564","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_2d26f429-adc8-4056-9cc0-73101772531e.jpg?v=1707506787","url":"https:\/\/danabiosci.com\/products\/new-product-232220","provider":"Dana Bioscience","version":"1.0","type":"link"}