{"product_id":"new-product-231902","title":"DOK7 polyclonal antibody","description":"\u003cp\u003eThe downstream of kinase family (Dok1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1\/2\/3, Dok-4\/5\/6 and Dok-7. Through its interaction with musclespecific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA)-recessively inherited disorders characterized by muscle weakness.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47663224848664,"sku":"BS62278","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_35678150-b69c-4fe5-ba53-d632a1c27062.jpg?v=1707505247","url":"https:\/\/danabiosci.com\/products\/new-product-231902","provider":"Dana Bioscience","version":"1.0","type":"link"}