{"product_id":"new-product-231787","title":"GPR173 polyclonal antibody","description":"\u003cp\u003eNectin-4\/Poliovirus Receptor-Like 4 (PVRL4) is a type-I transmembrane glycoprotein that belongs to the immunoglobulin superfamily and promotes cell-cell adhesion by serving as a major component of adherens junctions. The extracellular domain of Nectin-4, which contains an Ig variable-like domain (V) and two Ig constant-like domains (C), mediates binding to the measles virus and to neighboring cells through trans heterophilic interactions with Nectin-1. Unlike other nectin family members, which are widely expressed in adult tissues, Nectin-4 expression in humans is largely restricted to the placenta. Research studies have demostrated that Nectin-4 is overexpressed in a variety of human solid tumors of the pancreas, breast, lung, and ovary. Due to its restricted expression pattern in normal human tissues, Nectin-4 may serve as a novel diagnostic and therapeutic target for a variety of human tumors.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"101ul \/ Rabbit \/ Human,Rat","offer_id":47663140143384,"sku":"BS62424","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_c3d36058-5980-4396-993a-5110f94536ea.jpg?v=1707504722","url":"https:\/\/danabiosci.com\/products\/new-product-231787","provider":"Dana Bioscience","version":"1.0","type":"link"}