{"product_id":"new-product-231095","title":"PRG2 polyclonal antibody","description":"\u003cp\u003eThe eosinophil major basic protein (EMBP), also designated MBP, PRG2, proteoglycan 2, BMPG, or bone marrow natural killer cell activator, is a constituent of the crystalline core of the eosinophil granule. High levels of the pro-EMBP are present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A\u003cbr\u003e\n(PAPPA), angiotensinogen (AGT) and C3δγ. EMBP may influence antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and may play a role in immune hypersensitivity reactions. EMBP stimulates an Src kinase-dependent activation of class I (A) phosphoinositide 3-kinase and, in turn, activation of protein kinase C ζ in neutrophils. EMBP transcription is under regulation by novel combinatorial interactions of GATA-1, PU.1, and C\/EBPε isoforms.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse","offer_id":47662991704344,"sku":"BS67313","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_d122d4a0-a8d9-42f7-8bd7-9ad33f8f5cab.jpg?v=1707501385","url":"https:\/\/danabiosci.com\/products\/new-product-231095","provider":"Dana Bioscience","version":"1.0","type":"link"}