{"product_id":"new-product-231074","title":"CD36 polyclonal antibody","description":"\u003cp\u003eCD36 is a class B scavenger receptor composed of short amino-terminal and carboxy-terminal cytoplasmic domains, two transmembrane domains, and a large glycosylated extracellular domain . The CD36 receptor has many diverse ligands and cellular functions and is expressed by multiple cell types, including monocytes, macrophages, platelets, endothelial cells, adipocytes, and some epithelial cells . Binding of thrombospondin-1 (TSP-1) to CD36 facilitates the inhibition of angiogenesis by TSP-1 . CD36 also binds lipids and enables their transport into cells . In macrophages, CD36 acts as a receptor for oxidized LDL (Ox-LDL) and is responsible for Ox-LDL internalization, which contributes to development of atherosclerosis . The CD36 receptor participates in the innate immune response by acting as a pattern recognition receptor for lipid components of bacterial cell walls and fungal beta-glucans . CD36 likely influences signaling by interacting with other cell surface receptors including TLRs, integrins, and tetraspanins . Phorbol 12-myristate 13-acetate (PMA)\/ 12-O-tetradecanoylphorbol-13-acetate (TPA) induces CD36 expression in the THP-1 monocyte cell line .\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse, Rat","offer_id":47662983577880,"sku":"BS67331","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_df8ab9fb-0739-4452-91a0-bf3673f01cd7.jpg?v=1707501281","url":"https:\/\/danabiosci.com\/products\/new-product-231074","provider":"Dana Bioscience","version":"1.0","type":"link"}