{"product_id":"new-product-230890","title":"IL-11Rα (D361) polyclonal antibody","description":"\u003cp\u003eThe pleiotropic cytokine, IL-11, has been shown to have proliferative and differentiation effects on lymphopoietic, myeloid and erythroid cells. IL-11 also has the inhibiting effect of repressing adipogenesis in vitro. The IL-11α receptor, IL-11Rα, is a member of the class 1 subgroup of the cytokine receptor family and exhibits structural similarity to the α subunits of the human ciliary neurotrophic factor (CNTF) and the mouse IL-6 receptor. It is speculated that the IL-11Rα regulates the proliferation and\/or differentiation of skeletogenic progenitor and mesenchymal cells. Coexpression of gp130 and IL-11α is necessary for high-affinity binding of IL-11 to IL-11Rα. It has also been found that coexpression of IL-11Rα and gp130 is required for proper stimulation of Ba\/F3 cells to differentiate into macrophage in response to IL-11.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662962082072,"sku":"BS9265","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_963df763-a8de-4cf2-84e4-38f870362f68.jpg?v=1707500454","url":"https:\/\/danabiosci.com\/products\/new-product-230890","provider":"Dana Bioscience","version":"1.0","type":"link"}