{"product_id":"new-product-230709","title":"CD90 monoclonal antibody","description":"\u003cp\u003eThe Thy1\/CD90 cell surface antigen is a GPI-anchored, developmentally regulated protein involved in signaling cascades that mediate neurite outgrowth, T cell activation, tumor suppression, apoptosis, and fibrosis. Thy1\/CD90 is highly expressed on the surface of adult neurons and is thought to play a role in modulating adhesive and migratory events, such as neurite extension. Decreased Thy1\/CD90 mRNA and protein expression is associated with the development of epithelial ovarian cancer, suggesting a role as a putative tumor suppressor gene of human ovarian cancer. Research studies indicate that Thy1\/CD90 knockout mice have impaired cutaneous immune responses and abnormal retinal development. Thy1\/CD90 is epigenetically regulated or deregulated in some disease states, such as pulmonary fibrosis. The potentially reversible hypermethylation of the Thy1\/CD90 promoter offers the possibility of novel therapeutic options in this disease.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":47662917091608,"sku":"MB65821","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_cca98c99-b9bf-475d-b7fe-bfa479a66376.jpg?v=1707499627","url":"https:\/\/danabiosci.com\/products\/new-product-230709","provider":"Dana Bioscience","version":"1.0","type":"link"}