{"product_id":"new-product-230675","title":"CD137 Rat monoclonal antibody","description":"\u003cp\u003eTNFRSF9 is a member of the tumor necrosis factor receptor superfamily. It is also called 4-1BB or CD137. 4-1BB\/CD137\/TNFRSF9 is expressed in activated CD4+ and CD8+ T cells, natural killer cells and dendritic cells. The ligand 4-1BBL\/CD137L\/TNFSF9 on antigen presenting cells binds to 4-1BB\/CD137\/TNFRSF9 and costimulates the activation of T cells. The binding of agonistic antibodies to 4-1BB\/CD137\/TNFRSF9 also leads to costimulation for T cell activation. Studies have shown the effectiveness of targeting 4-1BB\/CD137\/TNFRSF9 by its agonistic antibodies in cancer immunotherapy.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rat \/ Mouse","offer_id":47662911684888,"sku":"MB65858","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_82769737-1eb6-4367-af6f-33c7672fbc1a.jpg?v=1707499473","url":"https:\/\/danabiosci.com\/products\/new-product-230675","provider":"Dana Bioscience","version":"1.0","type":"link"}