{"product_id":"new-product-230511","title":"BOB1 monoclonal antibody","description":"\u003cp\u003eB cell Oct binding factor-1 (BOB-1\/OBF-1) is a B cell restricted transcriptional coactivator. BOB-1 facilitates transactivation of immunoglobulins and other B cell specific genes through the binding and activation of the transcription factors Oct-1 and Oct-2 . Research studies have demonstrated that BOB-1 expression is required for antigen-dependent B cell maturation. In pathological conditions such as classical Hodgkin disease, loss of BOB-1 expression is thought, in part, to contribute to the defect in immunoglobulin gene expression by Hodgkin and Reed Sternberg cells. In the context of multiple myeloma, overexpression of BOB-1 has been shown to contribute to malignant plasma cell growth, in part, through enhanced transactivation of TNFRSF17\/BCMA.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":47662886912280,"sku":"MB66023","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_ca442edd-fcef-48fc-b65a-4931548cf931.jpg?v=1707498741","url":"https:\/\/danabiosci.com\/products\/new-product-230511","provider":"Dana Bioscience","version":"1.0","type":"link"}