{"product_id":"new-product-230395","title":"Claudin 7 monoclonal antibody","description":"\u003cp\u003eThe Claudin superfamily consists of many structurally related proteins in humans . These proteins are important structural and functional components of tight junctions in paracellular transport . Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues . Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and Junction adhesion molecule . Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands . Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions . mRNA studies indicate that Claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis . The gene encoding human Claudin-7 maps to chromosome 17p13 .\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":47662874853656,"sku":"MB66138","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_2b5c5460-e687-41be-8441-a18b5aea27aa.jpg?v=1707498187","url":"https:\/\/danabiosci.com\/products\/new-product-230395","provider":"Dana Bioscience","version":"1.0","type":"link"}