{"product_id":"new-product-230352","title":"CD79a monoclonal antibody","description":"\u003cp\u003eAntigen receptors found on the surface of B cells contain a heterodimeric signaling component composed of CD79A and CD79B, also known as Ig α and Ig β, respectively . Presence of this receptor complex is essential for B cell development and function . Together these two proteins and the associated B cell receptor (BCR) initiate intracellular signaling following antigen binding . An immunoreceptor tyrosine-based activation motif (ITAM) found in the CD79A intracellular region appears to be important for its function . Antigen binding precedes formation of the CD79A and CD79B heterodimer and subsequent activation of receptor associated kinases . Research has shown that CD79A is a marker for B-lineage lymphoblastic leukemia (8). Additionally, investigators have found that mutations in the CD79A (MB1) gene are associated with abnormally low levels of functional B cell receptors in some cases of chronic B cell lymphocytic leukemia .\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":47662870298904,"sku":"MB66181","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_a8d72505-3632-467b-9966-ba0c422ad0b5.jpg?v=1707497981","url":"https:\/\/danabiosci.com\/products\/new-product-230352","provider":"Dana Bioscience","version":"1.0","type":"link"}