{"product_id":"new-product-230308","title":"Beta-catenin monoclonal antibody","description":"\u003cp\u003eβ-catenin is a key downstream effector in the Wnt signaling pathway . It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis . CK1 phosphorylates β-catenin at Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3β (4-6). GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41 . Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":47662862139672,"sku":"MB66225","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_0601a97c-83b0-4056-90ee-9dcb80bc59ed.jpg?v=1707497760","url":"https:\/\/danabiosci.com\/products\/new-product-230308","provider":"Dana Bioscience","version":"1.0","type":"link"}