{"product_id":"new-product-230198","title":"PKC θ (phospho-T538) polyclonal antibody","description":"\u003cp\u003eMembers of the protein kinase C (PKC) family of serine\/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types. PKC theta is a member of the PKC family, and its predominant expression in hematopoietic cells suggests that it may play a role in signal transduction and growth regulatory pathways unique to these cells. PKC theta is a Ca(2+)-independent PKC isoform that is selectively expressed in T lymphocytes (and muscle), and it is thought to play an important role in T cell receptor-induced activation. Among several PKC isoenzymes expressed in T cells, PKC theta is unique in being rapidly recruited to the site of TCR clustering. It has been shown that PKC theta is essential for TCR-mediated T-cell activation, but it is dispensable during TCR-dependent thymocyte development.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662738407704,"sku":"AP0292","price":348.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_dea103d1-a47e-4468-b5ea-d1c513fbc1dc.jpg?v=1707493671","url":"https:\/\/danabiosci.com\/products\/new-product-230198","provider":"Dana Bioscience","version":"1.0","type":"link"}