{"product_id":"new-product-230197","title":"AhR (phospho-S36) polyclonal antibody","description":"\u003cp\u003eThe Aryl Hydrocarbon Receptor (AHR), also known as the dioxin receptor, is a ligand-activated helix\/loop\/helix transcription factor found in a variety of vertebrate species. The known ligands for AHR are foreign planar aromatic compounds, such as polycyclic aromatic compounds and halogenated aromatic compounds such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).Unlike the steroid\/thyroid hormone receptors, there is no known physiological ligand for the AH Receptor. Studies indicate that in non-ligand activated cells, AHR is found complexed with HSP90 predominantly in the cytoplasm. Upon binding to an agonist, the ligand-activated AHR is believed to transform to a nuclear, DNA binding form. This transformation process appears to involve dissociation of HSP90 from AHR followed by formation of a heterodimer with AHR nuclear translocator protein (Arnt). The AHR-ligand complex appears to initiate gene transcription of cytochrome P450 1A1.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662738342168,"sku":"AP0302","price":348.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_0f17f81f-4008-4f46-9f9a-ec6469f116c2.jpg?v=1707493668","url":"https:\/\/danabiosci.com\/products\/new-product-230197","provider":"Dana Bioscience","version":"1.0","type":"link"}