{"product_id":"new-product-229824","title":"AKT2 (phospho-S474) polyclonal antibody","description":"\u003cp\u003eAKT, also known as protein kinase B (PKB), is a 57 kDa serine\/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662668382488,"sku":"BS4720","price":348.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_c692774c-9fa0-4f2b-ae0a-8d52d4126fc4.jpg?v=1707491678","url":"https:\/\/danabiosci.com\/products\/new-product-229824","provider":"Dana Bioscience","version":"1.0","type":"link"}